Osteoporotic vertebral compression fractures (OVCF) are common among the elderly. [1]Percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) can quickly relieve pain, but the incidence of refracture after surgery will increase, which will affect the prognosis. [2]This article reviews the latest progress of refracture after OVCF surgery, pointing out that refracture is not just a single factor but a result of the interaction of multiple factors, such as patients, techniques, images, and management. [3]The core mechanisms include changes in biomechanics, reduced bone quality, and impaired healing. [4]Based on this, the article emphasizes the importance of individualized risk assessment and proposes the integration of imaging, biomechanical, and clinical data to construct predictive models, aiming to optimize surgical strategies and improve patients' long-term health outcomes.

Keyu Zeng, Xingda Cai, Weijian Zhang, Dingsheng Zha. Research Progress on Risk Factors for Post-operative Re-fracture after Osteoporotic Vertebral Compression Fracture Surgery. International Journal of Frontiers in Medicine (2026), Vol. 8, Issue 1: 14-21. https://doi.org/10.25236/IJFM.2026.080102.

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