Academic Journal of Materials & Chemistry, 2026, 7(1); doi: 10.25236/AJMC.2026.070106.
Ying Zhang1, Yuhuan Liu1
1School of Biomedical and Chemical Engineering, Liaoning Institute of Science and Technology, Benxi, China
Ginseng, a perennial herb of the Araliaceae family, is widely used in the pharmaceutical and food industries due to its main active ingredient, ginsenosides. However, the extraction of ginsenosides generates a large quantity of by-products such as marc, which are often discarded, leading to resource wastage and environmental pressure. Studies have found that these by-products are rich in ginseng polysaccharides, which possess various biological activities such as immunomodulatory, antitumor, neuroprotective, and antioxidant effects, demonstrating high development value. This paper systematically reviews the extraction and purification processes of polysaccharides from ginsenoside extraction by-products, including crude extraction methods, refining and purification techniques, and structural identification methods, analyzes their main biological functional properties, and discusses the current status and prospects of their development and application in the field of functional foods, thereby providing a theoretical basis for the comprehensive utilization of ginseng resources and promoting the development of the industry for high-value transformation of ginseng by-products.
Ginsenosides, By-products, Ginseng polysaccharides, Purification process, Functional foods
Ying Zhang, Yuhuan Liu. Purification of Polysaccharides from By-products of Ginsenoside Extraction and Development of Functional Foods. Academic Journal of Materials & Chemistry (2026), Vol. 7, Issue 1: 34-40. https://doi.org/10.25236/AJMC.2026.070106.
[1] Liang Yi, Zhao Shu. Progress in understanding of ginsenoside biosynthesis[J]. Plant Biology, 2008, 10(4): 415-421.
[2] Tao Ruizhi, Lu K, Zong G, et al. Ginseng polysaccharides: Potential antitumor agents[J]. Journal of ginseng research, 2023, 47(1): 9-22.
[3] Zhou Guolin, Wang C Z, Mohammadi S, et al. Pharmacological Effects of Ginseng: Multiple Constituents and Multiple Actions on Humans[J]. The American journal of Chinese medicine, 2023, 51(5): 1085-1104.
[4] Liu Silu, Geng J, Chen W, et al. Isolation, structure, biological activity and application progress of ginseng polysaccharides from the Araliaceae family[J]. International journal of biological macromolecules, 2024, 276(Pt 2): 133925.
[5] Li Wei. Integrating tradition and innovation: Health industry opportunities for ginseng with foods and medicines[J]. Chinese Herbal Medicines, 2024, 16(4): 487-488.
[6] Zhang Shuai, Liu F, Li J, et al. A 4.7-kDa polysaccharide from Panax ginseng suppresses Aβ pathology via mitophagy activation in cross-species Alzheimer's disease models[J]. Biomedicine & pharmacotherapy, 2023, 167: 115442.
[7] Xiong Boyu, Liu R, Zhi X, et al. Valorization and evaluation of acidic and neutral polysaccharides from Panax ginseng processing residues for the mitigating effects on skin aging[J]. Food research international, 2025, 221(Pt 3): 117462.
[8] Qin Si-Yi, Lai J M, Jia B, et al. Research progress in preparations of Panax ginseng[J]. China Journal of Chinese Materia Medica, 2024, 49(7): 1717-1724.